≥98% SR9011 Powder

≥98% SR9011 Powder

$440$19,599

  • Alias: SR-9011; SR 9011.
  • CAS ID: 1379686-29-9.
  • Melting point: 243~244°C.
  • Appearance: off-white fine powder.
SKU: AAS050-1
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  • Description
  • Steroid Calculator
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Description

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SR9011 Powder Overview.

SR-9011 (SR9011) (powder) is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues.

Must-Know For SR9011 Powder.

Once your SR9011 powder is received, please store it in a vacuumed and sealed dry container and put it in cool area at around 0~4°C. The shelf life is 3 years if stored properly.

  • SR9011 powder off-white fine powder. It’s ready for making capsules or oral liquids once received.
  • SR9011 is attractive as performance-enhancing substance due to its REV-ERB agonist effects and thus circadian rhythm modulation activity.
  • The common strength was made for SR9011 oral liquids is 10mg/ml with powder and necessary solvents.

More About SR9011 (Powder).

SR9009 and SR9011 are both attractive as performance-enhancing substances due to their REV-ERB agonist effects and thus circadian rhythm modulation activity.

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

900x180 brewing guide-steroid powder to oil calculator

Brewing guide - steroid powder to oil calculator

 

How to use this Anabolic Steroid calculator

To calculate 40ml of oil at 100mg/ml with 2% ba and 18%
(1) In the oil field enter 40
(2) In the dosage field enter 100
(3) Unless you know for sure, usually leave powder weight alone.
(4)  BA Concentration is set at  2%, if you wanted less, then change it accordingly
(5) BB concentration is set at  18%, if you wanted less, then change it accordingly
(6) You should now have the results :
Oil = 29mls
Powder = 4 grams
BA = 0.80ml's
BB = 7.20mls


Notes: BB is not always needed in certain experiments BB = benzyl benzoate BA = benzyl alcohol
Enter Amount Required
Total oil in mL  40ml = 40
Dosage in mg/mL   250mg/ml = 250
Powder Weight  normally .75 to .94
BA percent  2% = 0.02
BB percent   20% = 0.20
 
Results - Amounts Needed
GSO / Carrier Oil - - ml's
Powder - - grams
BA - - ml's
BB - - ml's

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